Anti-DACH1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55311.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Transcription factor that is involved in regulation of organogenesis. Seems to... more

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Product information "Anti-DACH1"

Protein function: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin- dependent kinase inhibitors, including the p27Kip1 promoter. Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain. [The UniProt Consortium]

Keywords:	Anti-DACH, Anti-DACH1, Anti-Dach1, Anti-Dachshund homolog 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55311

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse, rat
Immunogen:	Recombinant protein of Human DACH1
MW:	79 kD
Format:	Antigen Affinity Purified