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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay120550-1 | 1 each | - |
6 - 10 business days* |
422.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The cysteinyl leukotrienes (cysLTs, LTC4, LTD4, and LTE4) contract airway and pulmonary vascular... more
Product information "Anti-CysLT2 Receptor (C-Term)"
The cysteinyl leukotrienes (cysLTs, LTC4, LTD4, and LTE4) contract airway and pulmonary vascular smooth muscle, increase vascular permeability, and stimulate mucus secretion, thereby playing a major role in asthma. LTC4, LTD4, and LTE4 mediate their actions via at least two receptors designated CysLT1 and CysLT2. Cloning of the human CysLT2 receptor reveals it is a 346 amino acid protein with 38% homology to the CysLT1 receptor. The rank order of binding for leukotrienes to the cloned receptor, as determined using a radioligand binding assay, is LTC4 = LTD4 >> LTE4. The mRNA for the human CysLT2 receptor is expressed in lung macrophages, airway smooth muscle, cardiac Purkinje cells, adrenal medulla cells, peripheral blood leukocytes, spleen, placenta, and brain.Synonyms: Cysteinyl-Leukotriene Receptor 2. Immunogen: Synthetic peptide from the C-terminal region of human CysLT2 Receptor. Formulation: (Request formulation change), Peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: ELISA, FC, IHC, and WB. Cross Reactivity: (-) CysLT1 receptor. UniProt Accession #: Q9NS75. Origin: Animal/Rabbit.
Keywords: | Anti-CYSLT2, Anti-HPN321, Anti-HPN321, Anti-CYSLTR2, Anti-CysLTR2, Anti-hGPCR21, Anti-CysLTR2, Anti-hGPCR21, Anti-PSEC0146, Anti-G-protein coupled receptor HG57, Anti-G-protein coupled receptor HG57, Anti-Cysteinyl leukotriene receptor 2, Anti-Cysteinyl l |
Supplier: | Cayman Chemical |
Supplier-Nr: | 120550 |
Properties
Application: | ELISA, FC, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Immunogen: | Synthetic peptide from the C-terminal region of human CysLT2 Receptor |
Format: | Solid |
Database Information
KEGG ID : | K04323 | Matching products |
UniProt ID : | Q9NS75 | Matching products |
Gene ID | GeneID 57105 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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