Anti-CysLT2 Receptor (N-Term)

Anti-CysLT2 Receptor (N-Term)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay120560-1 1 each -

3 - 10 business days*

324.00€
 
The cysteinyl leukotrienes (cysLTs) (LTC4, LTD4, and LTE4) contract airway and pulmonary vascular... more
Product information "Anti-CysLT2 Receptor (N-Term)"
The cysteinyl leukotrienes (cysLTs) (LTC4, LTD4, and LTE4) contract airway and pulmonary vascular smooth muscle, increase vascular permeability and stimulate mucus secretion, thereby playing a major role in asthma. LTC4, LTD4, and LTE4 mediate their actions via at least 2 receptors designated CysLT1 and CysLT2. Cloning of the human CysLT2 receptor reveals it is a 346 amino acid protein with 38% homology to the human CysLT1 receptor. The rank order of binding for leukotrienes to the cloned receptor, as determined using a radioligand binding assay, is LTC4 = LTD4 >> LTE4. The mRNA for the human CysLT2 receptor is expressed in lung macrophages, airway smooth muscle, cardiac Purkinje cells, adrenal medulla cells, peripheral blood leukocytes, spleen, placenta, and brain. Synonyms: Cysteinyl-Leukotriene Receptor 2. Immunogen: Synthetic peptide from the N-terminal region of human CysLT2. Formulation: Peptide affinity-purified antibody. Storage Buffer: TBS, pH 7.4, when reconstituted in 500 µl double distilled water. Host: Rabbit. Applications: ELISA, FC, and WB. Cross Reactivity: (-) CysLT1. UniProt Accession #: Q9NS75. Origin: Animal/Rabbit.
Keywords: Anti-CYSLT2, Anti-HPN321, Anti-HPN321, Anti-CYSLTR2, Anti-CysLTR2, Anti-hGPCR21, Anti-CysLTR2, Anti-hGPCR21, Anti-PSEC0146, Anti-G-protein coupled receptor HG57, Anti-G-protein coupled receptor HG57, Anti-Cysteinyl leukotriene receptor 2, Anti-Cysteinyl l
Supplier: Cayman Chemical
Supplier-Nr: 120560

Properties

Application: ELISA, FC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Immunogen: Synthetic peptide from the N-terminal region of human CysLT2
Format: Solid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H316, H319
P Phrases: P264, P280, P305+351+338, P332+313, P337+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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