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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
034180-APC.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1... more
Product information "Anti-CPSF4, ID (CPSF4, CPSF30, NAR, NEB1, Cleavage and polyadenylation specificity factor subunit 4,"
Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-CPSF4, Anti-Neb-1, Anti-CPSF30, Anti-No arches homolog, Anti-CPSF 30 kDa subunit, Anti-NS1 effector domain-binding protein 1, Anti-Cleavage and polyadenylation specificity factor subunit 4 |
Supplier: | United States Biological |
Supplier-Nr: | 034180-APC |
Properties
Application: | FLISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | APC |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | CPSF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102~132 amino acids from the Central region of human CPSF4. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K14404 | Matching products |
UniProt ID : | O95639 | Matching products |
Gene ID | GeneID 10898 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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