Anti-CKAP5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57427.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Binds to the plus end of microtubules and regulates microtubule dynamics and... more

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Product information "Anti-CKAP5"

Protein function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch- TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448). [The UniProt Consortium]

Keywords:	Anti-CKAP5, Anti-Ch-TOG, Anti-KIAA0097, Anti-Cytoskeleton-associated protein 5, Anti-Colonic and hepatic tumor overexpressed gene protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57427

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant protein of Human CKAP5
MW:	225 kD
Format:	Antigen Affinity Purified