Anti-ch-TOG

Anti-ch-TOG
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-970A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A301-970A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A301-970A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Binds to the plus end of microtubules and regulates microtubule dynamics and... more
Product information "Anti-ch-TOG"
Protein function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch- TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448). [The UniProt Consortium]
Keywords: Anti-CKAP5, Anti-Ch-TOG, Anti-KIAA0097, Anti-Cytoskeleton-associated protein 5, Anti-Colonic and hepatic tumor overexpressed gene protein
Supplier: Bethyl Laboratories
Supplier-Nr: A301-970A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse)
Immunogen: synthetic peptide. The epitope recognized by A301-970A-T maps to a region between residue 1425 and 1475 of human colonic and hepatic tumor over-expressed protein using the numbering given in entry NP_001008938.1 (GeneID 9793).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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