Anti-CEP152

Anti-CEP152
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-479A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-479A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-479A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Necessary for centrosome duplication, the function seems also to involve CEP63,... more
Product information "Anti-CEP152"
Protein function: Necessary for centrosome duplication, the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles (PubMed:20852615). [The UniProt Consortium]
Keywords: Anti-CEP152, Anti-Cep152, Anti-KIAA0912, Anti-Centrosomal protein of 152 kDa
Supplier: Bethyl Laboratories
Supplier-Nr: A302-479A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-479A-T maps to a region between residue 50 and 100 of human centrosomal protein 152kDa using the numbering given in entry EAW77355.1 (GeneID 22995).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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