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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A302-480A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A302-480A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
Protein function: Necessary for centrosome duplication, the function seems also to involve CEP63,... more
Product information "Anti-CEP152"
Protein function: Necessary for centrosome duplication, the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure (PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles (PubMed:20852615). [The UniProt Consortium]
Keywords: | Anti-CEP152, Anti-Cep152, Anti-KIAA0912, Anti-Centrosomal protein of 152 kDa |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A302-480A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: gorilla, chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A302-480A-T maps to a region between residue 825 and 875 of human centrosomal protein 152kDa using the numbering given in entry EAW77355.1 (GeneID 22995). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K16728 | Matching products |
UniProt ID : | O94986 | Matching products |
Gene ID | GeneID 22995 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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