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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00065-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00065 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Required for kinetochore function and chromosome segregation in mitosis.... more
Product information "Anti-CENP-F/Mitosin (IHC)"
Protein function: Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia. [The UniProt Consortium]
Keywords: | Anti-CENPF, Anti-CENP-F, Anti-Mitosin, Anti-AH antigen, Anti-Centromere protein F, Anti-Kinetochore protein CENPF |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00065 |
Properties
Application: | ICC-IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: orangutan, gorilla, chimpanzee, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00065 maps to a region between residues 1800 and 1850 of human Centromere Protein F using the numbering given in SwissProt entry P49454 (GeneID 1163). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11499 | Matching products |
UniProt ID : | P49454 | Matching products |
Gene ID | GeneID 1063 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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