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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES10518.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
| ELK-ES10518.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
similarity:Belongs to the protein kinase superfamily., Protein function: Cyclin-dependent kinase... more
Product information "Anti-CDK12"
similarity:Belongs to the protein kinase superfamily., Protein function: Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Nucleus . Nucleus speckle . Colocalized with nuclear speckles throughout interphase. .
| Keywords: | Anti-CRK7, Anti-CDK12, Anti-CrkRS, Anti-hCDK12, EC=2.7.11.22, Anti-Cyclin-dependent kinase 12, Anti-CDC2-related protein kinase 7, Anti-Cell division protein kinase 12, Anti-Cdc2-related kinase, arginine/serine-rich, CDK12 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES10518 |
Properties
| Application: | WB, ELISA |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, rat |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 50-130 |
| MW: | 163 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K08819 | Matching products |
| UniProt ID : | Q9NYV4 | Matching products |
| Gene ID | GeneID 51755 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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