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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES8389.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES8389.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor... more
Product information "Anti-CD88"
function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family., Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high- affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Cell membrane , Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .
Keywords: | Anti-C5aR, Anti-C5AR, Anti-CD88, Anti-C5a-R, Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a anaphylatoxin chemotactic receptor 1, CD88 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES8389 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | The antiserum was produced against synthesized peptide derived from the N-terminal region of human C5AR1. AA range:1-50 |
MW: | 39 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K04010 | Matching products |
UniProt ID : | P21730 | Matching products |
Gene ID | GeneID 728 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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