- Search results for K04010
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120 products were found matching "K04010"!
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Item number: ELK-ELK4243.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse C5aR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse C5aR1. Next,...
Keywords: | CD88, C5aR, C5ar, C5ar1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1 |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: G-HDBS0099.100
Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high- affinity site on the extracellular...
Keywords: | Anti-CD88, Anti-C5aR, Anti-C5AR, Anti-C5AR1, Anti-C5a-R, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
Application: | FC |
Host: | Human |
Species reactivity: | human |
399.00€
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Item number: Cay35840-10
PMX-53 is a macrocyclic complement 5a (C5a) peptidomimetic and an antagonist of the C5a receptor (IC50 = 0.3 µM). It inhibits C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). PMX-53 (10 mg/kg, p.o.) inhibits vascular leakage, PMN infiltration, and peritoneal...
Keywords: | 3D53, AcF-[OPdChaWR], AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg], (6->2)-lactam,... |
Application: | C5a receptor antagonist |
CAS | 514814-99-4 |
MW: | 896.1 D |
From 81.00€
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Item number: ARG22558.100
Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor...
Keywords: | Anti-C5aR, Anti-C5ar, Anti-CD88, Anti-C5ar1, Anti-C5a-R, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
Application: | FC, FA, IHC (frozen) |
Host: | Rat |
Species reactivity: | mouse |
608.00€
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Item number: ARG54294.50
Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a...
Keywords: | Anti-C5AR, Anti-CD88, Anti-C5aR, Anti-C5a-R, Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
Application: | FC, IP, WB, IHC (paraffin) |
Host: | Mouse |
Species reactivity: | human, bovine, ferret, rabbit |
520.00€
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Item number: Cay23896-2.5
L-156,602 is an antagonist of the complement component 5A (C5a) receptor (IC50 = 1.7 µg/L in a radioligand binding assay using neutrophil membranes). It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria. L-156,602 has anti-inflammatory activity in mice, decreasing inflammation...
Keywords: | PD 124966,... |
Application: | C5a receptor antagonist |
CAS | 125228-51-5 |
MW: | 841 D |
From 300.00€
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Item number: Cay13607-1
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR, IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX-205 is also brain penetrant and reduces neuroinflammation and neurodegeneration in an animal...
Keywords: | N2-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-L-arginine, (5->1)-lactam,... |
Application: | C5a receptor antagonist |
MW: | 839.1 D |
From 261.00€
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Item number: Cay21231-1
W-54011 is an orally bioavailable, nonpeptide antagonist of complement component 5a receptor 1 (C5aR), also known as cluster of differentiation 88 (CD88). W-54011 inhibits 125I-rhC5a binding in neutrophils (Ki = 2.2 nM) and C5a-mediated intracellular Ca2+ mobilization (IC50 = 3.1 nM). W-54011 is selective and does...
Keywords: | N-[[4-(dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide,... |
Application: | C5a Receptor Antagonist |
CAS | 405098-33-1 |
MW: | 493.1 D |
From 54.00€
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Item number: E-AB-18573.120
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the...
Keywords: | Anti-C5aR, Anti-CD88, Anti-C5AR, Anti-C5a-R, Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 71.00€
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Item number: Cay24448-1
NDT 9513727 is a competitive antagonist of the C5a receptor (C5aR, IC50 = 11.6 nM for human recombinant receptors) that has inverse agonist activity in a GTPgamma[35S] assay. It is selective for human recombinant over rat and mouse recombinant C5aRs (IC50 = >10 µM for both) but does have activity at macaque and...
Keywords: | N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine |
Application: | Competitive C5a receptor (CD88) antagonist |
CAS | 439571-48-9 |
MW: | 573.7 D |
From 43.00€
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Item number: NSJ-RQ5707
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a. It functions as a complement receptor. C5a receptor modulates inflammatory responses, obesity, development...
Keywords: | Anti-CD88, Anti-C5ar, Anti-C5aR, Anti-C5ar1, Anti-C5a-R, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
Application: | WB, IF, FC, Direct ELISA |
Host: | Rabbit |
Species reactivity: | mouse |
755.00€
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Item number: G-CAB1900.100
WB 1:500 - 1:2000. Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the...
Keywords: | Anti-C5aR, Anti-CD88, Anti-C5AR, Anti-C5a-R, Anti-C5AR1, Anti-C5a anaphylatoxin chemotactic receptor, Anti-C5a... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
From 352.00€
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