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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2405-02L1.100 | 100 µg | - | - |
3 - 19 business days* |
916.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Integrin a5, is a 140-150kD integrin alpha chain that forms dimers with at least five beta chains... more
Product information "Anti-CD49e (CD49 Antigen-like Family Member E, Fibronectin Receptor alpha, FNRA, Integrin alpha-F, I"
Integrin a5, is a 140-150kD integrin alpha chain that forms dimers with at least five beta chains including b1, 3, 5, 6, and 8. It is a 1018aa residue type I membrane protein with a large 962aa extracellular domain (ECD) and a short 32aa cytoplasmic tail. The N-terminal region of Integrin a5, which is important for ligand binding, contains seven FG-GAP (phenylalanyl-glycyl and glycyl-alanyl-prolyl) consensus repeats that fold into a b-propeller domain. Furin cleavage of the Integrin a5 ECD occurs after Gly 889, generating a disulfide-linked, heteromeric subunit Integrin a5 chain. Integrin a5-containing integrins bind multiple ECM molecules, including Vitronectin, Osteopontin, MMP-2, and TSP. The ECD of human Integrin 5 shares 92aa sequence identity with mouse Integrin a5 ECD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-Integrin alpha-5 heavy chain, Anti-Integrin alpha-5 light chain, Anti-CD49 antigen-like family member E, Anti-Fibronectin receptor subunit alpha |
Supplier: | United States Biological |
Supplier-Nr: | C2405-02L1 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 11n34 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa42-995 from human Integrin a5/CD49e expressed in CHO cells (P08648). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06484 | Matching products |
UniProt ID : | P08648 | Matching products |
Gene ID | GeneID 3678 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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