Anti-CD49e, clone SNAKA51

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG10853.100	100 µg		-	-	6 - 14 business days*		608.00€

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Protein function: Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and... more

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Product information "Anti-CD49e, clone SNAKA51"

Protein function: Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430). [The UniProt Consortium]

Keywords:	Anti-FNRA, Anti-ITGA5
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG10853

Properties

Application:	FA, ICC, IF, WB
Antibody Type:	Monoclonal
Clone:	SNAKA51
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Whole cells corresponding to Human CD49e