Anti-CD45, clone 2B11

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55974.50	50 µg		-	-	6 - 14 business days*		608.00€

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Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the... more

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Product information "Anti-CD45, clone 2B11"

Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. [The UniProt Consortium]

Keywords:	Anti-T200, Anti-CD45, Anti-L-CA, Anti-PTPRC, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein phosphatase C
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55974

Properties

Application:	ELISA, FC, ICC, IF, IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	2B11
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Isolated neoplastic cells
Format:	Purified