Anti-CD35 / CR1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66541.100	100 µg		-	-	6 - 14 business days*		584.00€

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Protein function: Membrane immune adherence receptor that plays a critical role in the capture... more

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Product information "Anti-CD35 / CR1"

Protein function: Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069). Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation (PubMed:2963069). Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d (PubMed:2972794, PubMed:8175757). Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells (PubMed:25742728). [The UniProt Consortium]

Keywords:	Anti-CR1, Anti-C3BR, Anti-CD35, Anti-C3b/C4b receptor, Anti-Complement receptor type 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66541

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthetic peptide around the internal region of Human CD35 / CR1
MW:	224 kD
Format:	Antigen Affinity Purified