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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
DC-853.403.020 | 100 µg (100 µl) | - |
3 - 8 business days* |
379.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Specificity: The CD35 antigen, CR1, is a complement component receptor with specificity for C3b,... more
Product information "Anti-CD35 (human), Unconjugated Clone UJ11 [Mouse]"
Specificity: The CD35 antigen, CR1, is a complement component receptor with specificity for C3b, C4b and iC3b, Format: PBS with 15 mM sodium azide (Ph7.4), Working Dilution: We recommend that each laboratory determine an optimum working titre for use in its particular application, Storage: Store at +2-8°C. For longer storage, freeze aliquots, Application Notes: Suitable for Flow Cytometry Protein function: Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed:2963069). Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation (PubMed:2963069). Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d (PubMed:2972794, PubMed:8175757). Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells (PubMed:25742728). [The UniProt Consortium]
Keywords: | Mouse Anti-Human CD35 Monoclonal Antibody, Unconjugated Clone UJ11, Anti-CR1, Anti-CD35, Anti-C3BR, Anti-C3b/C4b receptor, Anti-Complement receptor type 1 |
Supplier: | Diaclone |
Supplier-Nr: | 853.403 |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | UJ11 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Database Information
KEGG ID : | K04011 | Matching products |
UniProt ID : | P17927 | Matching products |
Gene ID | GeneID 1378 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H300, H310, H410, EUH032 |
P Phrases: | P262, P264, P270, P273, P280, P321, P330, P391, P301+P310, P302+P352, P361+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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