Anti-CD2AP, clone 5F8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59346.50	50 µg		-	-	6 - 14 business days*		520.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Seems to act as an adapter protein between membrane proteins and the actin... more

Close menu

Product information "Anti-CD2AP, clone 5F8"

Protein function: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260). [The UniProt Consortium]

Keywords:	Anti-CD2AP, Anti-Adapter protein CMS, Anti-CD2-associated protein, Anti-Cas ligand with multiple SH3 domains
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59346

Properties

Application:	FC, IHC (paraffin), WB
Antibody Type:	Monoclonal
Clone:	5F8
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant protein corresponding to K253-K337 of Human CD2AP
MW:	71 kD
Format:	Antigen Affinity Purified