Anti-CD253 / TRAIL Monoclonal Antibody (Clone:2E5)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-30-1201-0.1	100 µg		-		3 - 11 business days*		580.00€

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Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II... more

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Product information "Anti-CD253 / TRAIL Monoclonal Antibody (Clone:2E5)"

Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2). Protein function: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. [The UniProt Consortium]

Keywords:	Anti-APO2L, Anti-CD253, Anti-Apo-2L, Anti-TNFSF10, Anti-Apo-2 ligand, Anti-Protein TRAIL, Anti-TNF-related apoptosis-inducing ligand, Anti-Tumor necrosis factor ligand superfamily member 10, Anti-CD253 / TRAIL Monoclonal Antibody (Clone:2E5)
Supplier:	Abeomics
Supplier-Nr:	30-1201

Properties

Application:	FA
Antibody Type:	Monoclonal
Clone:	2 E 5
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant soluble fragment (aa 95-281) of human TRAIL.
Format:	Affinity Purified