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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1755-100 | 100 tests | - |
3 - 11 business days* |
713.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide... more
Product information "Anti-CD203c Monoclonal Antibody (Clone:NP4D6)-APC Conjugated"
CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies. Protein function: Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (PubMed:29717535). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells. Has also alkaline phosphodiesterase activity (PubMed:11342463). [The UniProt Consortium]
Keywords: | Anti-NPP3, Anti-ENPP3, Anti-CD203c, Anti-NPPase, Anti-E-NPP 3, Anti-PD-Ibeta, Anti-Nucleotide diphosphatase, Anti-Phosphodiesterase I beta, Anti-Nucleotide pyrophosphatase, Anti-Alkaline phosphodiesterase I, Anti-CD203c Monoclonal Antibody (Clone:NP4D6)-A |
Supplier: | Abeomics |
Supplier-Nr: | 30-1755 |
Properties
Application: | FC, ICC |
Antibody Type: | Monoclonal |
Clone: | NP4D6 |
Conjugate: | APC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | HEK-293 cells transfected with human CD203c |
Database Information
KEGG ID : | K01513 | Matching products |
UniProt ID : | O14638 | Matching products |
Gene ID | GeneID 5169 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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