135 products were found matching "K01513"!

ENPP3 inhibitor 5J is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) and ENPP3 (IC50s = 0.59 and 0.62 µM, respectively, for the human enzymes).Formal Name: 2-(2-(1H-indol-3-yl)acetamido)phenyl trifluoromethanesulfonate. Molecular Formula: C17H13F3N2O4S. Formula Weight:...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ENPP1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ENPP1. Next,...

Protein function: Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (PubMed:29717535). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and...

ENPP1 inhibitor C is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1, IC50 = 0.26 µM in a cell-free assay). It is selective for ENPP1 over ENPP2-7 at 10 µM. ENPP1 inhibitor C decreases ENPP1 activity in MDA-MB-231 human breast and C6 rat glioma cancer cells when used at a concentration of...

Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) is a type II transmembrane glycoprotein with nucleotide pyrophosphatase and phosphodiesterase enzyme activities. It is expressed in skeletal, adipose, hepatic, renal, cardiac, and placental tissues, as well as pancreatic islets, salivary...

Protein function: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. [The UniProt Consortium]

Protein function: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. [The UniProt Consortium]

Protein function: By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP,...

Protein function: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. [The UniProt Consortium]

Protein function: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Ectonucleotide pyrophosphatase/phosphodiesterase 1 Protein function: Nucleotide pyrophosphatase that generates diphosphate (PPi) and functions in bone mineralization and soft tissue...