Anti-CD178 / Fas-L, clone 14C2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG23266.100	100 µg		-	-	6 - 14 business days*		608.00€

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Protein function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic... more

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Product information "Anti-CD178 / Fas-L, clone 14C2"

Protein function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (PubMed:27806260). [The UniProt Consortium]

Keywords:	Anti-FASLG, Anti-APT1LG1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG23266

Properties

Application:	ELISA, FC, IP
Antibody Type:	Monoclonal
Clone:	14C2
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Format:	Purified

Database Information

KEGG ID :	K04389 \| Matching products
UniProt ID :	P48023 \| Matching products
Gene ID	GeneID 356 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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