Anti-CB2 Receptor FITC

The central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors are G protein-coupled receptors (GPCRs) that bind the active component of cannabis, Delta9-tetrahydrocannabinol, as well as anandamide which is an endogenous CB receptor ligand. This antibody has been raised against a sequence between the N-terminal and the first transmembrane domain of the protein of the human CB2 receptor. Conserved amino acids between the CB1 and CB2 receptors in this region are minimal. Human and mouse CB2 receptors exhibit 82% homology at the amino acid level over the complete protein. The CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells.Synonyms: Cannabinoid Receptor 2, CNR2. Immunogen: Synthetic peptide from the N-terminal region of human CB2 receptor. Formulation: (Request formulation change), 500 µl of peptide affinity-purified antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: FC and IF. UniProt Accession #: P34972. Origin: Animal/Rabbit.