71 products were found matching "K04278"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CNR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CNR2. Next,...

Cannabidiol (Cay-90080) is an analytical reference material categorized as a phytocannabinoid. Unlike Delta9-THC (Cay-ISO60157, Cay-12068), cannabidiol is non-psychoactive. This product is intended for research and forensic applications.Formal Name:...

AM630 binds selectively to cannabinoid 2 (CB2) over CB1 receptors with Ki values of 31.2 and 5,152 nM, respectively. AM630 acts as an inverse agonist at CB2 receptors, attenuating the antinociceptive effects of a number of cannabinoids, and as a weak partial agonist at CB1 receptors. It decreases proliferation and...

The CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells. The CB1 and CB2 receptors are G-protein coupled receptors that bind the active component of cannabis, Delta9-tetrahydrocannabinol, as well as anandamide which is an endogenous CB receptor ligand. This...

SR 144528 is a cannabinoid 2 (CB2) receptor antagonist (Ki = 0.6 nM). It is selective for CB2 over CB1 receptors in CHO cells expressing the human receptors (Ki = 437 nM). SR 144528 reverses CP 55,940-induced inhibition of forskolin-induced adenylyl cyclase activity in CHO cells expressing human CB2 receptors (EC50...

Dihomo-gamma-linolenoyl ethanolamide is an endocannabinoid containing dihomo-gamma-linoleate in place of the arachidonate moiety of AEA. Dihomo-gamma-linolenoyl ethanolamide binds to recombinant human CB1 and CB2 receptors with Ki values of 857 and 598 nM, respectively. Its specific role and relative importance as a...

Tetrahydromagnolol is an agonist of cannabinoid (CB) receptors, an antagonist of GPR55 (KB = 13.3 µM in a beta-arrestin translocation assay), and a major metabolite of magnolol (Cay-14233). Tetrahydromagnolol binds to the CB1 and CB2 receptors (Kis = 2.26 and 0.416 µM, respectively, for the human receptor) and...

PF-03550096 is a synthetic cannabinoid (CB) that selectively targets the peripheral CB2 receptor over the central CB1 receptor (Kis = 7.9 and 1,500 nM for human isoforms, respectively). It shows similar selectivity for inhibiting forskolin-stimulated cAMP production in CHO cells expressing human CB1 and CB2...

SDB-006 N-phenyl analog is a cannabimimetic indole that binds the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with EC50 values of 21 and 140 nM, respectively. It was discovered during research of the related compound JWH 018 adamantyl carboxamide (Cay-9001193), which has been sold illicitly...

UR-144 (Cay-11502) and XLR11 (Cay-11565) are potent synthetic cannabinoids (CBs) that have been identified as adulterants of herbal products. Azidoindolene 1 is structurally similar to UR-144, XLR11, and a number of additional synthetic CBs with a hydrazide linking the tetramethylcyclopropyl group to the...

A-796260 (Cay-11606) is a synthetic cannabinoid (CB) that shows high selectivity for the CB2 receptor (Ki = 0.77 nM) over the CB1 receptor (Ki = 2,100 nM). It also shows efficacy in vivo in models of inflammatory, post-operative, neuropathic, and osteoarthritic pain, activities which are selectively blocked by CB2...

MDA 77 is a selective inverse agonist of the human peripheral cannabinoid (CB2) receptor that demonstrates an EC50 value of 5.8 nM at CB2 and no activity at central cannabinoids (CB1) receptor in functional binding assays. The in vivo activity of this compound has not been reported. This product is intended for...