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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C0026-08.100 | 100 µg | - | - |
3 - 19 business days* |
880.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ErbB3 is a member of the EGFR/erbB receptor tyrosine kinase family. ErbB3 lacks intrinsic kinase... more
Product information "Anti-c-erbB3, CT (HER3), clone 6D175"
ErbB3 is a member of the EGFR/erbB receptor tyrosine kinase family. ErbB3 lacks intrinsic kinase activity due to an amino acid substitution within the ATP binding site. Upon heterodimerization with the other erbB family members, erbB3 becomes phosphorylated at multiple tyrosine residues that represent docking sites for downstream signaling proteins, e.g., PI3K, grb7 and shc. The erbB3 cytoplasmic domain contains 6 docking sites for PI3K. Thus, erbB3 is a potent activator of the PI3K/PKB signaling pathway. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5ug/ml for HRPO/ECL detection, Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer., Optimal dilution to be determined by researcher. Positive Control, included: Cell lysate from untreated SW620 cells. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-HER3, Anti-ERBB3, EC=2.7.10.1, Anti-Proto-oncogene-like protein c-ErbB-3, Anti-Receptor tyrosine-protein kinase erbB-3, Anti-Tyrosine kinase-type cell surface receptor HER3 |
Supplier: | United States Biological |
Supplier-Nr: | C0026-08 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 6D175 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to a portion of C-terminal ErbB3 (Her3). |
Database Information
KEGG ID : | K05084 | Matching products |
UniProt ID : | P21860 | Matching products |
Gene ID | GeneID 2065 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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