Anti-BRUCE

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-Z94	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-BRUCE Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-BRUCE"

Anti-BRUCE Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. BRUCE antibody is human specific. Multiple isoforms of BRUCE are known to exist. Protein function: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [The UniProt Consortium]

Keywords:	Anti-BIRC6, Anti-BRUCE, Anti-APOLLON, Anti-KIAA1289, EC=6.3.2.-, Anti-Baculoviral IAP repeat-containing protein 6, Anti-Ubiquitin-conjugating BIR domain enzyme apollon, Anti-BIR repeat-containing ubiquitin-conjugating enzyme
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-Z94

Properties

Application:	ELISA, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	17 amino acid synthetic peptide near the C-terminus of human BRUCE.
Format:	Purified