Anti-BMP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F43310-0.08ML	80 µl		-	-	3 - 10 business days*		326.00€
NSJ-F43310-0.4ML	400 µl		-	-	3 - 10 business days*		702.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene belongs to the... more

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Product information "Anti-BMP2"

In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. Protein function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). [The UniProt Consortium]

Keywords:	Anti-BMP2, Anti-BMP2A, Anti-BMP-2, Anti-BMP-2A, Anti-Bone morphogenetic protein 2, Anti-Bone morphogenetic protein 2A, BMP2 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	F43310

Properties

Application:	WB, FC, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	A portion of amino acids 260-289 from the human protein was used as the immunogen for this BMP2 antibody.
Format:	Purified