131 products were found matching "K21283"!

Induces cartilage and bone formation. (www.uniprot.org) Produced in E.coli. Homodimeric, non-glycosylated polypeptide chain containing 115 amino acids. The ED50 as determined by the cytolysis of MC3T3-E1 cells is less then 50 ng/ml.

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bone morphogenetic protein 2b (Bmp2b) is a secreted signaling molecule belonging to the transforming growth factor-beta (TGF-beta) superfamily, and it plays a pivotal role in embryonic development, cell fate specification, and morphogenesis. In zebrafish (Danio...

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically...

Protein function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in...

Protein function: Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast...

Bone morphogenetic protein 2 (BMP2), a member of the transforming growth factor-beta (TGF-beta) super-family, is one of the main chondrogenic growth factors involved in cartilage regeneration. BMP2 is known to induce chondrogenic differentiation in various types of stem cells in vitro. However, BMP2 also induces...

Human Bone Morphogenetic Protein-2 (BMP-2) is a bone-growth regulatory factor and belongs to the transforming growth factor-beta (TGF-beta) superfamily. Human Bone Morphogenetic Protein-2 (BMP-2) is synthesized as large precursor molecule (Met1-Arg396, with a signal peptide from Met1 to Gly23), propeptide...

BMP-2 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor beta (TGF-beta ) superfamily, BMPs were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and...

BMP-2 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor beta (TGF-beta ) superfamily, BMPs were originally identified as protein regulators of cartilage and bone formation. However, they have since been shown to be involved in embryogenesis and...

Human recombinant BMP-2 produced in HEK cells is a glycosylated disulfide-linked homodimer, having a molecular weight range of 30-38kDa due to glycosylation. BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein induces bone formation. BMP2 is a candidate gene for the...

Natural and recombinant mouse BMP-2. There is no detectable cross-reactivity with other relevant proteins. Protein function: Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation...

Induces cartilage and bone formation. (www.uniprot.org) Produced in E.coli as a monomeric, non-glycosylated, polypeptide chain containing 115 amino acids (fragment 283-396).