Anti-BMP-2

Item number	Size	Manual	Delivery time	Price
E-AB-33728.20	20 µl	-	7 - 16 business days*	71.00€
E-AB-33728.60	60 µl	-	7 - 16 business days*	143.00€
E-AB-33728.120	120 µl	-	7 - 16 business days*	238.00€
E-AB-33728.200	200 µl	-	7 - 16 business days*	396.00€

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This gene encodes a member of the transforming growth factor-beta (TGFB) superfamily. The encoded... more

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Product information "Anti-BMP-2"

This gene encodes a member of the transforming growth factor-beta (TGFB) superfamily. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which induces bone and cartilage formation. Protein function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). [The UniProt Consortium]

Keywords:	Anti-BMP2, Anti-BMP-2, Anti-BMP2A, Anti-BMP-2A, Anti-Bone morphogenetic protein 2, Anti-Bone morphogenetic protein 2A, BMP-2 Polyclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-33728

Properties

Application:	WB, IHC (paraffin), ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthesized peptide derived from the C-terminal region of human BMP-2.
Format:	Purified