Anti-Ataxin 1 / ATXN1

Anti-Ataxin 1 / ATXN1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32138 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ataxin-1 is a protein that in humans is... more
Product information "Anti-Ataxin 1 / ATXN1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1 (ATXN1), a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes. Protein function: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development. [The UniProt Consortium]
Keywords: Anti-ATX1, Anti-ATXN1, Anti-Ataxin-1, Anti-Spinocerebellar ataxia type 1 protein, Ataxin 1 Antibody / ATXN1
Supplier: NSJ Bioreagents
Supplier-Nr: R32138

Properties

Application: WB, IHC (paraffin), IF, FC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Amino acids ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE of human Ataxin 1
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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