Anti-ARHGEF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG58958.50	50 µl		-	-	6 - 14 business days*		520.00€

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Protein function: Seems to play a role in the regulation of RhoA GTPase by guanine... more

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Product information "Anti-ARHGEF1"

Protein function: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation. [The UniProt Consortium]

Keywords:	Anti-Sub1.5, Anti-ARHGEF1, Anti-p115RhoGEF, Anti-p115-RhoGEF, Anti-Rho guanine nucleotide exchange factor 1, Anti-115 kDa guanine nucleotide exchange factor
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG58958

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant fusion protein corresponding to aa. 783-912 of Human ARHGEF1 (NP_004697.2)
MW:	102 kD
Format:	Affinity Purified