Anti-p115-RhoGEF

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-701A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-701A	100 µl		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Seems to play a role in the regulation of RhoA GTPase by guanine... more

Close menu

Product information "Anti-p115-RhoGEF"

Protein function: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation. [The UniProt Consortium]

Keywords:	Anti-Sub1.5, Anti-ARHGEF1, Anti-p115RhoGEF, Anti-p115-RhoGEF, Anti-Rho guanine nucleotide exchange factor 1, Anti-115 kDa guanine nucleotide exchange factor
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-701A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: gorilla, chimpanzee, white-tufted-ear marmoset, african elephant, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-701A-T maps to a region between residue 275 and 325 of human 115 kDa Rho guanine nucleotide exchange factor using the numbering given in entry NP_004697.2 (GeneID 9138).
Format:	Antigen Affinity Purified