Anti-Androgen Receptor

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66478.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Steroid hormone receptors are ligand-activated transcription factors that... more

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Product information "Anti-Androgen Receptor"

Protein function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. [The UniProt Consortium]

Keywords:	Anti-AR, Anti-DHTR, Anti-Androgen receptor, Anti-Dihydrotestosterone receptor, Anti-Nuclear receptor subfamily 3 group C member 4
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66478

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Synthetic peptide derived from Human Androgen Receptor
MW:	99 kD
Format:	Antigen Affinity Purified