273 products were found matching "K08557"!

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...

LGD 3033 is an androgen receptor agonist. It selectively binds to the androgen receptor (Ki = 0.9 nM for the human receptor) over mineralocorticoid, glucocorticoid, and progesterone receptors (Kis = 1,261, 581, and 136 nM, respectively, for the human receptors). It also selectively induces reporter transcription in...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat AR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat AR. Next, Avidin...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse AR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse AR. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AR. Next,...

ARV-110 is a proteolysis-targeting chimera (PROTAC) that contains a cereblon ligand 1-derivative connected to an androgen receptor (AR) ligand by a linker region. It reduces AR levels in VCaP prostate cancer cells in a time- and concentration-dependent manner. ARV-110 (1 µM) decreases VCaP cancer cell proliferation....

Trestolone acetate (Cay-31974) is an analytical reference standard categorized as a synthetic anabolic androgenic steroid. Formulations containing trestolone acetate have been used to enhance physical performance in athletes. Trestolone acetate is regulated as a Schedule III compound in the United States. This...

Nandrolone decanoate (Cay-32546) is an analytical reference standard categorized as an anabolic androgenic steroid. Nandrolone decanoate is a prodrug form of nandrolone (Cay-21173) that has been used to enhance physical performance in athletes. Nandrolone decanoate is regulated as a Schedule III compound in the...

Androstenedione (exempt preparation) (Cay-37897) is an analytical reference standard categorized as an anabolic androgenic steroid. Androstenedione is a precursor of testosterone (Cay-ISO60154, Cay-ISO00154, Cay-15645) and estrone (Cay-10006485). Androstenedione is regulated as a Schedule III compound in the United...

Dihydrotestosterone (Cay-15874) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including dihydrotestosterone, have been used to enhance physical performance in athletes. Dihydrotestosterone is regulated as a Schedule III compound in the United States. This...

Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental...

11-keto Testosterone (CRM) (Cay-9002654) is a certified reference material that is structurally categorized as an androgen. It is a significant hormone in certain fish, regulating the development of sexual development and behavior. 11-keto Testosterone binds the stickleback kidney androgen receptor (EC50 = 43 nM)....