404 products were found matching "K08557"!

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...

Testosterone enanthate (exempt preparation) (Cay46044) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone enanthate is a prodrug form of testosterone (CayISO60154, CayISO00154, Cay15645). It has been found in performance-enhancing drug (PED) samples seized by law...

Testosterone cypionate (exempt preparation) (Cay46045) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone cypionate is a prodrug form of testosterone (CayISO60154, CayISO00154, Cay15645). It has been detected in hair samples from competition athletes and plasma samples...

Testosterone isobutyrate (Cay41937) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone isobutyrate is a prodrug form of testosterone (CayISO60154, CayISO00154, Cay15645). Testosterone isobutyrate is regulated as a Schedule III compound in the United States. This product...

ARD-266 is a proteolysis-targeting chimera (PROTAC) containing an androgen receptor antagonist conjugated to a VHL ligand via a piperidine-alkyne linker. It induces degradation of the androgen receptor in LNCaP, VCaP, and 22Rv1 prostate cancer cells with half-maximal degradation concentration (DC50) values of 0.54,...

Rezvilutamide is a non-steroidal androgen receptor antagonist. It reduces secretion of prostate-specific androgen (PSA) from LNCaP prostate cancer cells (IC50 = 22 nM) and reduces proliferation of the same cells (IC50 = 33 nM). Formulations containing rezvilutamide have been used in the treatment of prostate...

MK-0773 is a selective androgen receptor modulator (SARM). It selectively binds to the androgen receptor (AR, IC50 = 6.6 nM) over the glucocorticoid and progesterone receptors (IC50s = >2 µM for both). It is a partial agonist of AR that increases AR-dependent transcription in a reporter assay using MDA-MB-453 cells...

1 mg/ml in 1X PBS, BSA free, sodium azide free. Androgen receptor (AR), encoded by the AR gene and also known as nuclear receptor subfamily 3 group C member 4 (NR3C4), is a ligand-activated nuclear hormone receptor that mediates cellular responses to androgens such as testosterone and dihydrotestosterone. AR...

0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. Androgen receptor (AR), encoded by the AR gene and also known as nuclear receptor subfamily 3 group C member 4 (NR3C4), is a ligand-activated nuclear hormone receptor that mediates cellular responses to androgens such as testosterone and dihydrotestosterone. AR...

Antibody in 1X PBS with 0.05% BSA, 0.05% sodium azide. Androgen receptor (AR), encoded by the AR gene and also known as nuclear receptor subfamily 3 group C member 4 (NR3C4), is a ligand-activated nuclear hormone receptor that mediates cellular responses to androgens such as testosterone and dihydrotestosterone. AR...

An internal standard for the quantification of enzalutamide by GC- or LC-MS. SMILES: S=C1N(C2=CC(F)=C(C=C2)C(NC([2H])([2H])[2H])=O)C(C)(C(N1C3=CC(C(F)(F)F)=C(C=C3)C#N)=O)C. InChi Code:...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: LNCap cells. Prostate carcinoma. Chromosome Location: Xq12. Protein Function: Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect...