Anti-Alpha 2a Adrenergic Receptor

Anti-Alpha 2a Adrenergic Receptor
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R31320 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The alpha 2A adrenergic receptor is a... more
Product information "Anti-Alpha 2a Adrenergic Receptor"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The alpha 2A adrenergic receptor is a member of the G protein-coupled receptor superfamily which include three highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. Protein function: Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. [The UniProt Consortium]
Keywords: Anti-ADRA2R, Anti-ADRA2A, Anti-Alpha-2AAR, Anti-Alpha-2A adrenoceptor, Anti-Alpha-2A adrenoreceptor, Anti-Alpha-2A adrenergic receptor, Anti-Alpha-2 adrenergic receptor subtype C10, Alpha 2a Adrenergic Receptor Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R31320

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: An amino acid sequence from the middle region of human alpha 2a Adrenergic Receptor (ILVYVRIYQIAKRRTR) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody (100% homologous in human, mouse and rat).
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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