Anti-ADRA2B, ID (Alpha-2B Adrenergic Receptor, Alpha-2B Adrenoreceptor, Alpha-2B Adrenoceptor, Alpha

Anti-ADRA2B, ID (Alpha-2B Adrenergic Receptor, Alpha-2B Adrenoreceptor, Alpha-2B Adrenoceptor, Alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A0906-65-PE.200 200 µl - -

1 - 19 business days

696.00€
 
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They... more
Product information "Anti-ADRA2B, ID (Alpha-2B Adrenergic Receptor, Alpha-2B Adrenoreceptor, Alpha-2B Adrenoceptor, Alpha"
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization, this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-ADRA2B, Anti-ADRA2L1, Anti-Alpha-2BAR, Anti-Alpha-2B adrenoceptor, Anti-Alpha-2B adrenoreceptor, Anti-Alpha-2B adrenergic receptor, Anti-Alpha-2 adrenergic receptor subtype C2
Supplier: United States Biological
Supplier-Nr: A0906-65-PE

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: Phycoerythrin
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide selected from the Center region of human ADRA2B (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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