Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-181A-T 10 µl (10 µg) -

6 - 10 business days*

A302-181A 100 µl (100 µg) -

6 - 10 business days*

Protein function: Involved in DNA damage response and double-strand break (DSB) repair. Component... more
Product information "Anti-Abraxas"
Protein function: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. [The UniProt Consortium]
Keywords: Anti-Protein FAM175A, Anti-BRCA1-A complex subunit Abraxas 1, Anti-Coiled-coil domain-containing protein 98
Supplier: Bethyl Laboratories
Supplier-Nr: A302-181A


Application: IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Rhesus Monkey, White-tufted-ear Marmoset, Crab-eating Macaque)
Immunogen: synthetic peptide. The epitope recognized by A302-181A-T maps to a region between residue 400 and 409 of human Abraxas (coiled-coil domain containing 98) using the numbering given in entry NP_620775.2 (GeneID 84142).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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