Anti-ABRA1, clone ABRA1-01

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG62665.100	100 µg		-	-	6 - 14 business days*		624.00€

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Protein function: Involved in DNA damage response and double-strand break (DSB) repair. Component... more

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Product information "Anti-ABRA1, clone ABRA1-01"

Protein function: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. [The UniProt Consortium]

Keywords:	Anti-ABRA1, Anti-FAM175A, Anti-Protein FAM175A, Anti-BRCA1-A complex subunit Abraxas, Anti-Coiled-coil domain-containing protein 98
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG62665

Properties

Application:	FC, IP, WB
Antibody Type:	Monoclonal
Clone:	ABRA1-01
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
Format:	Liquid