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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG44014.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647,... more
Product information "Anti-5HT2A Receptor"
Protein function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2- aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction. {ECO:0000269, PubMed:1330647, ECO:0000269, PubMed:18297054, ECO:0000269, PubMed:18703043, ECO:0000269, PubMed:19057895, ECO:0000269, PubMed:21645528, ECO:0000269, PubMed:22300836, ECO:0000269, PubMed:28129538}. [The UniProt Consortium]
Keywords: | Anti-HTR2, Anti-HTR2A, Anti-5-HT-2, Anti-5-HT-2, Anti-5-HT-2A, Anti-5-HT-2A, Anti-Serotonin receptor 2A, Anti-Serotonin receptor 2A, Anti-5-hydroxytryptamine receptor 2A, Anti-5-hydroxytryptamine receptor 2A |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG44014 |
Properties
Application: | ICC, IF, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide corresponding to aa. 1-105 of Human 5HT2A Receptor. (AYKSSQLQMGQKKNS) |
MW: | 53 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04157 | Matching products |
UniProt ID : | P28223 | Matching products |
Gene ID | GeneID 3356 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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