271 products were found matching "K04157"!

Psilocin (Cay-11864) is an analytical reference standard categorized as a tryptamine. Psilocin is the active metabolite of the psychedelic compound psilocybin (Cay-9003134, Cay-14041) and the synthetic tryptamine 4-acetoxy DMT (psilacetin, Cay-14056, Cay-35188). It induces the head-twitch response (HTR) in mice,...

Lumateperone is an atypical antipsychotic. It selectively binds to the serotonin (5-HT) receptor subtype 5-HT2A over 5-HT1A and 5-HT2C receptors (Kis = 0.54, 1,480, and 173 nM, respectively). Lumateperone also binds to dopamine D1, D2, and D4 receptors (Kis = 52, 32, and 108 nM, respectively), alpha1A- and...

Psilocybin (Cay-14041) is an analytical reference standard categorized as a tryptamine. It induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential. Psilocybin is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.Formal...

(+)-Fenfluramine is an agonist of the serotonin (5-HT) receptor subtypes 5-HT2B and 5-HT2C. It induces serotonin release from superfused midbrain synaptosome preparations isolated from wild-type mice, but not 5-HT2B-/- mice, when used at concentrations of 0. or 1 µM. (+)-Fenfluramine (3 or 10 mg/kg) reduces food...

Metabolite of clozapine. It is 5-HT2 serotonin receptor antagonist.

Serotonin-d4 is intended for use as an internal standard for the quantification of serotonin (Cay-14332) by GC- or LC-MS. Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the...

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...

Chlorpromazine (CPZ) is a typical antipsychotic and an antagonist of dopamine D2, D3, and D4 receptors (Kis = 0.66, 0.84, and 1.2 nM, respectively) as well as the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 1.8 nM). It is also an antagonist of histamine H1, alpha1a-, alpha2b-, and alpha2C-adrenergic, and M3...

Ritanserin is a selective antagonist of the serotonin (5-HT) receptor subtype, 5-HT2A. In a radioligand binding assay, ritanserin exhibits high selectivity for 5-HT2A over 5-HT1 receptors (IC50s = 0.9 nM and >1000 nM, respectively). It also demonstrates relatively low affinity for histamine H1, dopamine D2,...

Paliperidone is an atypical antipsychotic. It is an inverse agonist of dopamine D2 and D3 receptors (IC50s = 1 and 0.9 nM, respectively), as well as an antagonist at these receptors (Kis = 0.4 and 0.1 nM, respectively). Paliperidone also binds to alpha1- and alpha2-adrenergic receptors, histamine H1 receptors, and...

Clozapine is a partial agonist at the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 180 nM). It also binds to the 5-HT2A, 5-HT2C, 5-HT3, 5-HT6 and 5-HT7 receptors (Kis = 3.3, 13, 110, 4, and 21 nM, respectively), as well as the histamine H1 and alpha1-adrenergic receptors (Kis = 2.1 and 23 nM, respectively). It...

An analytical reference standard categorized as an anorectic, decreases oxycodone intake and has positive effects on self-administration and relapse vulnerability in rats, regulated as a Schedule IV compound in the United States, intended for research and forensic applications