Anti-Phospholipase A2 IIA, clone SCACC353

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56498.150	150 µg		-	-	6 - 14 business days*		640.00€

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Protein function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in... more

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Product information "Anti-Phospholipase A2 IIA, clone SCACC353"

Protein function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536). [The UniProt Consortium]

Keywords:	Anti-phospho-PLA2B, Anti-phospho-PLA2G2A, Anti-phospho-NPS-PLA2, Anti-phospho-GIIC sPLA2, Anti-phospho-Group IIA phospholipase A2, Anti-phospho-Phospholipase A2, membrane associated, Anti-phospho-Phosphatidylcholine 2-acylhydrolase 2A
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56498

Properties

Application:	WB, IHC, IP
Antibody Type:	Monoclonal
Clone:	SCACC353
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Human recombinant synovial Phospholipase A2 IIA
Format:	Antigen Affinity Purified