Anti-phospho-TSC1 (Thr416)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F48826-0.08ML	80 µl		-	-	3 - 10 business days*		326.00€
NSJ-F48826-0.4ML	400 µl		-	-	3 - 10 business days*		702.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. In complex with TSC2, inhibits the nutrient-mediated... more

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Product information "Anti-phospho-TSC1 (Thr416)"

In 1X PBS, pH 7.4, with 0.09% sodium azide. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. [The UniProt Consortium]

Keywords:	Anti-phospho-Tsc1, Anti-phospho-Kiaa0243, Anti-phospho-Hamartin, Anti-phospho-Tuberous sclerosis 1 protein homolog, Phospho-TSC1 Antibody (pT416)
Supplier:	NSJ Bioreagents
Supplier-Nr:	F48826

Properties

Application:	Dot Blot, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse
Immunogen:	This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT416 of mouse TSC1.
Format:	Purified