Anti-phospho-TSC1 (Thr310)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F48811-0.08ML	80 µl		-	-	3 - 10 business days*		326.00€
NSJ-F48811-0.4ML	400 µl		-	-	3 - 10 business days*		702.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought... more

Close menu

Product information "Anti-phospho-TSC1 (Thr310)"

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. [The UniProt Consortium]

Keywords:	Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-KIAA0243, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1 Antibody (pT310)
Supplier:	NSJ Bioreagents
Supplier-Nr:	F48811

Properties

Application:	Dot Blot, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	This phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT310 of human TSC1.
Format:	Purified