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![Anti-phospho-TNK1 (Tyr277)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES12620.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES12620.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein... more
Product information "Anti-phospho-TNK1 (Tyr277)"
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011], Protein function: Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm . Membrane , Peripheral membrane protein .
Keywords: | EC=2.7.10.2, Anti-phospho-CD38 negative kinase 1, Anti-phospho-Non-receptor tyrosine-protein kinase TNK1, TNK1 (phospho-Tyr277) rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES12620 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | Synthesized phosho peptide around human TNK1 (Tyr277) |
MW: | 75 kD |
Format: | Purified |
Database Information
KEGG ID : | K08885 | Matching products |
UniProt ID : | Q13470 | Matching products |
Gene ID | GeneID 8711 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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