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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES4942.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES4942.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein... more
Product information "Anti-phospho-Pragmin (Tyr413)"
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014], Protein function: Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth. Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism. Acts as a critical coactivator of Notch signaling. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .
Keywords: | Anti-phospho-SgK223, Anti-phospho-SGK223, Anti-phospho-Pragmin, Anti-phospho-Sugen kinase 223, Anti-phospho-Inactive tyrosine-protein kinase PRAG1, Anti-phospho-PEAK1-related kinase-activating pseudokinase 1, Pragmin (phospho Tyr413) rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES4942 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413) |
MW: | 175 kD |
Format: | Purified |
Database Information
KEGG ID : | K17537 | Matching products |
UniProt ID : | Q86YV5 | Matching products |
Gene ID | GeneID 157285 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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