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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES20162.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES20162.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase... more
Product information "Anti-phospho-MLK3 (Thr277+Ser281)"
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008], Protein function: Activates the JUN N-terminal pathway. Required for serum- stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen- stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.
Keywords: | EC=2.7.11.25, Anti-phospho-Mixed lineage kinase 3, Anti-phospho-Mitogen-activated protein kinase kinase kinase 11, Anti-phospho-Src-homology 3 domain-containing proline-rich kinase, MLK3 (Phospho Thr277+Ser281) rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES20162 |
Properties
Application: | WB, ELISA, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthesized peptide derived from human MLK3 (Phospho Thr277+Ser281) |
Format: | Purified |
Database Information
KEGG ID : | K04419 | Matching products |
UniProt ID : | Q16584 | Matching products |
Gene ID | GeneID 4296 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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