Anti-phospho-MEF2A (Thr312)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51543.50	50 µl		-	-	6 - 14 business days*		436.00€
ARG51543.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Transcriptional activator which binds specifically to the MEF2 element,... more

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Product information "Anti-phospho-MEF2A (Thr312)"

Protein function: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter. [The UniProt Consortium]

Keywords:	Anti-phospho-MEF2, Anti-phospho-MEF2A, Anti-phospho-Myocyte-specific enhancer factor 2A, Anti-phospho-Serum response factor-like protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51543

Properties

Application:	WB, IHC (paraffin), ICC, IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around phosphorylation site of threonine 312 (L-A-T(p)-P-V) derived from Human MEF2A
Format:	Affinity Purified