Anti-phospho-HDAC5 (Ser498)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51688.50	50 µl		-	-	6 - 14 business days*		436.00€
ARG51688.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of... more

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Product information "Anti-phospho-HDAC5 (Ser498)"

Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [The UniProt Consortium]

Keywords:	Anti-phospho-HD5, Anti-phospho-HDAC5, Anti-phospho-KIAA0600, EC=3.5.1.98, Anti-phospho-Antigen NY-CO-9, Anti-phospho-Histone deacetylase 5
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51688

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around phosphorylation site of serine 498 (T-Q-S(p)-S-P) derived from Human HDAC5/7
Format:	Affinity Purified