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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG66572.100 | 100 µg | - | - |
6 - 14 business days* |
584.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A... more
Product information "Anti-phospho-EphA7 (Tyr791)"
Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7. [The UniProt Consortium]
Keywords: | Anti-phospho-EHK3, Anti-phospho-EK11, Anti-phospho-hEK11, Anti-phospho-EHK-3, Anti-phospho-EPHA7, EC=2.7.10.1, Anti-phospho-EPH-like kinase 11, Anti-phospho-EPH homology kinase 3, Anti-phospho-Ephrin type-A receptor 7 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG66572 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Phosphospecific peptide around Tyr791 of Human EphA7 |
MW: | 112 kD |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K05108 | Matching products |
UniProt ID : | Q15375 | Matching products |
Gene ID | GeneID 2045 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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