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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES7125.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES7125.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport... more
Product information "Anti-phospho-ENaC beta (Thr615)"
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009], Protein function: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Apical cell membrane , Multi-pass membrane protein . Cytoplasmic vesicle membrane . Apical membrane of epithelial cells. .
Keywords: | Anti-phospho-ENaCB, Anti-phospho-SCNEB, Anti-phospho-SCNN1B, Anti-phospho-Beta-ENaC, Anti-phospho-Beta-NaCH, Anti-phospho-Epithelial Na(+) channel subunit beta, Anti-phospho-Nonvoltage-gated sodium channel 1 subunit beta, Anti-phospho-Amiloride-sensitive |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES7125 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human Nonvoltage-gated Sodium Channel 1 around the phosphorylation site of Thr615. AA range:581-630 |
MW: | 68 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K04825 | Matching products |
UniProt ID : | P51168 | Matching products |
Gene ID | GeneID 6338 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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